化合物简介
Glycogen Synthase Kinase-3ß is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. An oxothiadiazolidine-3-thione analogue that acts as a non-ATP competitive inhibitor of GSK-3ß ( IC50 =10uM).
基本信息
中文名称
2,4-二苄基-3-硫代-1,2,4-噻二唑烷-5-酮
英文名称
2,4-Dibenzyl-5-oxothiadiazolidine-3-thione
中文别名
英文别名
GSK-3InhibitorIII、GSK-3b Inhibitor III、2,4-Dibenzyl-3-thioxo-1,2,4-thiadiazolidin、2,4-dibenzyl-3-thioxo-[1,2,4]thiadiazolidin-5-one、2,4-dibenzyl-5-oxo-1,2,4-thiadiazolidine-3-thione、2,4-Bis(phenylMethyl)-3-thioxo-1,2,4-thiadiazolidin-5-one、2,4-Dibenzyl-3-thioxo-1,2,4-thiadiazolidin-5-on
CAS号
72966-20-2
分子式
C16H16N2OS2
分子量
316.441
精确质量
316.07
PSA
101.55
LOGP
3.7078
物化性质
熔点
91-95ºC
储存条件
-20ºC Freezer
