化合物简介
A metabolite of Tamoxifen, a nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxifen is a Protein Kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines.
基本信息
中文名称
他莫昔芬 N-氧化物
英文名称
tamoxifen N-oxide
中文别名
英文别名
(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine oxide、Ethanamine,2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-,N-oxide,(Z)、(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine N-Oxide、[14C]-Tamoxifen N-oxide、Tamoxifen N-oxide、[3H]-Tamoxifen N-oxide、2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine oxide
CAS号
75504-34-6
分子式
C26H29NO2
分子量
387.514
精确质量
387.22
PSA
38.66
LOGP
6.0296
物化性质
储存条件
Hygroscopic, -20ºC Freezer, Under Inert Atmosphere