(E)-2-Methyl-4-[(1R,5S,7R)-1-((R)-1-methyl-2-oxo-ethyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-but-2-enoic acid ethyl ester

CAS号：403507-10-8

英文名：(E)-2-Methyl-4-[(1R,5S,7R)-1-((R)-1-methyl-2-oxo-ethyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-but-2-enoic acid ethyl ester

分子式

C21H30F3NO4

熔点

密度

分子量

417.462

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

(E)-2-Methyl-4-[(1R,5S,7R)-1-((R)-1-methyl-2-oxo-ethyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-but-2-enoic acid ethyl ester

英文名称

(E)-2-Methyl-4-[(1R,5S,7R)-1-((R)-1-methyl-2-oxo-ethyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-but-2-enoic acid ethyl ester

中文别名

英文别名

CAS号

403507-10-8

分子式

C21H30F3NO4

分子量

417.462

精确质量

417.213

PSA

63.68

LOGP

4.1411

合成路线

共找到3条合成路线 >

945223-16-5

(1R,5S)-1-((R)-1-(benzyloxy)propan-2-yl)-7-(2-((tert-butyldimethylsilyl)oxy)ethyl)-6-azaspiro[4.5]dec-6-ene

403507-10-8

(E)-2-Methyl-4-[(1R,5S,7R)-1-((R)-1-methyl-2-oxo-ethyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-but-2-enoic acid ethyl ester

上游原料

共找到24个上游原料 >

403507-05-1

(2E,4E)-8-{(1R,2R)-1-tert-Butoxycarbonylamino-2-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-cyclopentyl}-2-methyl-octa-2,4-dienoic acid ethyl ester

857685-60-0

(2R)-2-((1R)-2-benzyloxy-1-methylethyl)-cyclopentanone

857685-70-2

1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-7-(R)-[2''-(tert-butyl-dimethyl-silanyloxy)-ethyl]-6-aza-5-(S)-spiro[4.5]decane

403507-06-2

(2E,4E)-8-{(1R,2R)-1-Amino-2-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-cyclopentyl}-2-methyl-octa-2,4-dienoic acid ethyl ester

857685-61-1

(2R)-2-((1R)-2-benzyloxy-1-methylethyl)-cyclopentanone oxime

857685-71-3

(1R,5S,7R)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-trifluoroacetyl-6-azaspiro[4.5]decane

下游产品

共找到3个下游商品 >

403507-86-8

(E)-4-[(1R,5S,7R)-1-((2E,5Z)-(1S,4S)-6-Chloro-4,8-dihydroxy-1-methyl-octa-2,5-dienyl)-6-aza-spiro[4.5]dec-7-yl]-2-methyl-but-2-enoic acid ethyl ester

403507-85-7

(E)-4-[(1R,5S,7R)-1-((2E,5Z)-(1S,4S)-6-Chloro-4,8-dihydroxy-1-methyl-octa-2,5-dienyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-2-methyl-but-2-enoic acid ethyl ester

403507-75-5

(E)-4-[(1R,5S,7R)-1-[(2E,5Z)-(S)-8-(tert-Butyl-dimethyl-silanyloxy)-6-chloro-1-methyl-4-oxo-octa-2,5-dienyl]-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-2-methyl-but-2-enoic acid ethyl ester

上游原料

(2E,4E)-8-{(1R,2R)-1-tert-Butoxycarbonylamino-2-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-cyclopentyl}-2-methyl-octa-2,4-dienoic acid ethyl ester (2R)-2-((1R)-2-benzyloxy-1-methylethyl)-cyclopentanone 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-7-(R)-[2''-(tert-butyl-dimethyl-silanyloxy)-ethyl]-6-aza-5-(S)-spiro[4.5]decane (2E,4E)-8-{(1R,2R)-1-Amino-2-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-cyclopentyl}-2-methyl-octa-2,4-dienoic acid ethyl ester (2R)-2-((1R)-2-benzyloxy-1-methylethyl)-cyclopentanone oxime (1R,5S,7R)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-trifluoroacetyl-6-azaspiro[4.5]decane (E)-4-{(1R,5S,7R)-1-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-6-aza-spiro[4.5]dec-7-yl}-2-methyl-but-2-enoic acid ethyl ester (1R)-1-((1R)-2-benzyloxy-1-methylethyl)-2-nitrocyclopentane (1R,5S,7R)-7-(2-hydroxyethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-trifluoroacetyl-6-azaspiro[4.5]decane (E)-4-[(1R,5S,7R)-1-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-2-methyl-but-2-enoic acid ethyl ester 3-[1'-(S)-nitro-2'-(R)-(2''-benzyloxy-1''-(R)-methylethyl)-cyclopentyl]-propionic acid methyl ester (1R,2S)-1-((1R)-2-benzyloxy-1-methylethyl)-2-(3-hydroxypropyl)-2-nitro-cyclopentane [(1R,5S,7R)-1-((R)-2-Benzyloxy-1-methyl-ethyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-acetaldehyde 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-2-(S)-(3''-iodo-propyl)-2-(S)-nitro-cyclopentane (1'R,5'S,7'R,1''R)-4-{1'-[2''-benzyloxy-1''-methyl-ethyl]-6'-trifluoroacetyl-6'-aza-5'-spiro[4.5]dec-7'-yl}-2-methylbut-2E-enoic acid ethyl ester (1R,5S)-1-((R)-1-(benzyloxy)propan-2-yl)-7-(2-((tert-butyldimethylsilyl)oxy)ethyl)-6-azaspiro[4.5]dec-6-ene (1R,2S)-1-((1R)-2-benzyloxy-1-methylethyl)-2-nitro-2-[3-(2-{2-[(tert-butyl)dimethylsilanyloxy]ethyl}-1,3-dithian-2-yl)propyl]-cyclopentane (3R,3aR,6aR)-3-methyl-hexahydrocyclopenta[b]furan-2-one 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-2-(S)-nitro-2-[6''-(tert-butyl-dimethyl-silanyloxy)-4''-oxo-hexyl]-cyclopentane (1S,5aR)-(R)-3-phenyl-hexahydro-1-oxa-3a-aza-cyclopenta[c]pentalen-4-one (3aR,6aS)-6a-Allyl-1-((R)-2-hydroxy-1-phenyl-ethyl)-hexahydro-cyclopenta[b]pyrrol-2-one (3aR,6aS)-6a-Allyl-hexahydro-cyclopenta[b]pyrrol-2-one (3aR,6aS)-6a-Allyl-2-oxo-hexahydro-cyclopenta[b]pyrrole-1-carboxylic acid tert-butyl ester (2E,4E)-5-Iodo-2-methyl-penta-2,4-dienoic acid ethyl ester

下游产品

(E)-4-[(1R,5S,7R)-1-((2E,5Z)-(1S,4S)-6-Chloro-4,8-dihydroxy-1-methyl-octa-2,5-dienyl)-6-aza-spiro[4.5]dec-7-yl]-2-methyl-but-2-enoic acid ethyl ester (E)-4-[(1R,5S,7R)-1-((2E,5Z)-(1S,4S)-6-Chloro-4,8-dihydroxy-1-methyl-octa-2,5-dienyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-2-methyl-but-2-enoic acid ethyl ester (E)-4-[(1R,5S,7R)-1-[(2E,5Z)-(S)-8-(tert-Butyl-dimethyl-silanyloxy)-6-chloro-1-methyl-4-oxo-octa-2,5-dienyl]-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-2-methyl-but-2-enoic acid ethyl ester