化合物简介
(2R)-3-Bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide is an intermediate in the synthesis of 4-Desacetamido-4-fluoro Andarine, a Selective Androgen Receptor Modulator (SARM) that has potential use for treatment of androgen related diseases such as muscle wasting and osteoporosis.
基本信息
中文名称
(2R)-3-溴-2-羟基-2-甲基-N-[4-硝基-3-(三氟甲基)苯基]丙酰胺
英文名称
3-Bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]p ropanamide
中文别名
(R)-3-溴-2-羟基-2-甲基-n-(4-硝基-3-(三氟甲基)苯基)丙酰胺
英文别名
(R)-3-bromo-1,2-propanediol、(R)-3-bromo-2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide、(2R)(-)-3-bromo-1,2-propanediol、N-[4-nitro-3-(trifluoromethyl)phenyl]-(2R)-3-bromo-2-hydroxy-2-methylpropanamide、(R)-3-BROMO-1,2-DIHYDROXYPROPANE、1,2-PROPANEDIOL,3-BROMO-,(R)、(R)-3-bromopropane-1,2-diol、R-3-bromo-N-(4-nitro-3-trifluoromethylphenyl)-2-hydroxy-2-methylpropionamide
CAS号
206193-18-2
分子式
C11H10BrF3N2O4
分子量
371.107
精确质量
369.978
PSA
98.64
LOGP
3.8707
物化性质
密度
1.753
沸点
491.7ºC at 760 mmHg
闪点
251.2ºC
合成路线
