化合物简介
Selegiline, also known as L-deprenyl is a substituted phenethylamine that at normal clinical doses it is a selective irreversible MAO-B inhibitor. In larger doses it loses its specificity and also inhibits MAO-A. It is available in pill form under many brand names and is used to reduce symptoms in early-stage Parkinson's disease. A transdermal patch (brand name, Emsam) is used to treat depression.
基本信息
中文名称
司来吉兰 盐酸盐
英文名称
(-)-selegiline
中文别名
司来吉兰
英文别名
Eldepryl、Jumex、(2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine、N-methyl-N-((R)-1-phenylpropan-2-yl)prop-2-yn-1-amine、Selegilina、Emsam、L-Deprenalin、Carbex、methyl(1-phenylpropan-2-yl)(prop-2-yn-1-yl)amine、Selegilinum、(S)-(+)-selegiline、Selegyline、Zelapar
CAS号
14611-51-9
分子式
C13H17N
分子量
187.281
精确质量
187.136
PSA
3.24
LOGP
2.1826
编号系统
UNII
2K1V7GP655
物化性质
密度
0.954g/cm3
沸点
272.5ºC at 760 mmHg
闪点
108.4ºC
折射率
1.528
蒸汽压
0.00606mmHg at 25°C
安全信息
危险品运输编码
UN 1851
海关编码
2921499090
危险类别
6.1(b)
包装等级
III