Mannostatin A Hydrochloride

Mannostatin A Hydrochloride

CAS号：134235-13-5

英文名：(1R,2R,3R,4S,5S)-4-amino-5-methylsulfanylcyclopentane-1,2,3-triol

分子式

C6H13NO3S

熔点

密度

分子量

179.237

沸点

溶解度

信号词

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

化合物简介

A potent glycosidase inhibitor that blocks Golgi processing mannosidase ll more effectively than swainsonine.

基本信息

中文名称

Mannostatin A Hydrochloride

英文名称

(1R,2R,3R,4S,5S)-4-amino-5-methylsulfanylcyclopentane-1,2,3-triol

中文别名

英文别名

1D-(1,2,3,4/5)-2,3,4-trihydroxy-5-(methylsulfanyl)cyclopentane-1-ammonium chloride、1-Cyclohexyl-1,2,3,4-tetrahydro-isoquinoline、1-cyclohexyl-TIQ、1-cy-hexyl-TIQ、(+)-mannostatin A monohydrochloride、mannostatin A hydrochloride

CAS号

134235-13-5

分子式

C6H13NO3S

分子量

179.237

精确质量

179.062

PSA

112.01

LOGP

-1.1581

合成路线

(1R,2R,3R,4R,5S)-1-(methylthio)-2,3,4-triacetoxy-5-(N-((R)-acetoxyphenylacetyl)amino)cyclopentane

(1R,2R,3R,4R,5S)-1-(methylthio)-2,3,4-triacetoxy-5-(N-((R)-acetoxyphenylacetyl)amino)cyclopentane

Mannostatin A Hydrochloride

Mannostatin A Hydrochloride

上游原料

共找到38个上游原料 >

5-deoxy-5-hydrazino-2,3-O-isopropylidene-D-ribono-1,5-lactam

5-deoxy-5-hydrazino-2,3-O-isopropylidene-D-ribono-1,5-lactam

cyclopenta-2,4-dien-1-yl(methyl)sulfane

cyclopenta-2,4-dien-1-yl(methyl)sulfane

(1S,4S,5R)-5-acetylamino-4-tert-butyldimethylsilyloxy-2-cyclopenten-1-ol

(1S,4S,5R)-5-acetylamino-4-tert-butyldimethylsilyloxy-2-cyclopenten-1-ol

4-O-[(tert-butyl)dimethylsilyl]-5-deoxy-5-hydrazino-2,3-O-isopropylidene-D-ribono-1,5-lactam

4-O-[(tert-butyl)dimethylsilyl]-5-deoxy-5-hydrazino-2,3-O-isopropylidene-D-ribono-1,5-lactam

(3aR,3bR,6aS,7R,7aR)-7-(methylthio)tetrahydro-3aH-spiro[[1,3]dioxolo[4',5':3,4]cyclopenta[1,2-d]oxazole-2,1'-cyclohexan]-5(3bH)-one

(3aR,3bR,6aS,7R,7aR)-7-(methylthio)tetrahydro-3aH-spiro[[1,3]dioxolo[4',5':3,4]cyclopenta[1,2-d]oxazole-2,1'-cyclohexan]-5(3bH)-one

(3S,4R,5S)-5-acetoxy-4-acetylamino-3-tert-butyldimethylsilyloxy-1-cyclopentene

(3S,4R,5S)-5-acetoxy-4-acetylamino-3-tert-butyldimethylsilyloxy-1-cyclopentene

上游原料

5-deoxy-5-hydrazino-2,3-O-isopropylidene-D-ribono-1,5-lactam (1S,4S,5R)-5-acetylamino-4-tert-butyldimethylsilyloxy-2-cyclopenten-1-ol 4-O-[(tert-butyl)dimethylsilyl]-5-deoxy-5-hydrazino-2,3-O-isopropylidene-D-ribono-1,5-lactam (3aR,3bR,6aS,7R,7aR)-7-(methylthio)tetrahydro-3aH-spiro[[1,3]dioxolo[4',5':3,4]cyclopenta[1,2-d]oxazole-2,1'-cyclohexan]-5(3bH)-one (3S,4R,5S)-5-acetoxy-4-acetylamino-3-tert-butyldimethylsilyloxy-1-cyclopentene (3aR,3bR,6aS,7R,7aR)-7-iodo-6-(4-methoxybenzyl)tetrahydro-3aH-spiro[[1,3]dioxolo[4',5':3,4]cyclopenta[1,2-d]oxazole-2,1'-cyclohexan]-5(3bH)-one 2D-(1,5/1,2,3,4)-1-O-acetyl-1,5-anhydro-4-O-[(tert-butyl)dimethylsilyl]-2,3-O-isopropylidenecyclopentane-1,1,2,3,4,5-hexol (1S,4S,5S)-5-acetylamino-4-methylthio-2-cyclopenten-1-ol (1R,2R,3R,4S,5R)-4-acetylamino-5-methylthiocyclopentane-1,2,3-triol (1S,4S,5S)-4-acetoxy-5-acetylamino-2-cyclopenten-1-ol (1R,4S,5S)-4-acetoxy-5-acetylamino-2-cyclopenten-1-ol 1D-(1,2,3,4/5)-4-O-[(tert-butyl)dimethylsilyl]-2,3-O-isopropylidene-5-O-(methylsulfonyl)-1-O-[(trifluoromethyl)sulfonyl]cyclopentane-1,2,3,4,5-pentol (1R,4S,5S)-5-acetylamino-4-methylthio-2-cyclopenten-1-ol 1D-(1,2,3,4/5)-4-O-[(tert-butyl)dimethylsilyl]-2,3-O-isopropylidenecyclopentane-1,2,3,4,5-pentol (3aR,3bR,6aS,7R,7aR)-7-iodotetrahydro-3aH-spiro[[1,3]dioxolo[4',5':3,4]cyclopenta[1,2-d]oxazole-2,1'-cyclohexan]-5(3bH)-one O-((3a'S,4'R,6a'S)-4',6a'-dihydro-3a'H-spiro[cyclohexane-1,2'-cyclopenta[d][1,3]dioxol]-4'-yl) S-methyl 4-methoxybenzylcarbonimidothioate (3S,4S,5R)-4-acetylamino-5-tert-butyldimethylsilyloxy-3-methylthio-1-cyclopentene 1D-(1,2,3/4,5)-3-O-[(tert-butyl)dimethylsilyl]-1,2-O-isopropylidene-5-(methylsulfanyl)-4-O-(methylsulfonyl)cyclopentane-1,2,3,4-tetrol 4-acetamido-3,5-diacetoxycyclopentene (1R,4S,7R)-3-(2-(R)-hydroxy-2-phenylacetyl)-7-(methylthio)-2-oxa-3-azabicyclo[2.2.1]hept-5-ene (3R,4R,5S)-4-acetylamino-3-tert-butyldimethylsilyloxy-5-ethoxycarbonyloxy-1-cyclopentene (3R,4R,5R)-4,5-dihydro-3,4-(O,O)-isopropylidene-5-mesyloxymethyl-2-(3H)-furanone 1D-(1,2,3/4,5)-1,2-O-isopropylidene-5-(methylsulfanyl)-4-O-(methylsulfonyl)cyclopentane-1,2,3,4-tetrol 4-amino-3,5-dihydroxycyclopentene 1D-(1,2,3/4,5)-1,2-O-isopropylidene-5-(methylsulfanyl)-4-O-(methylsulfonyl)-3-O-(2,2,2-trichloro-1-iminoethyl)cyclopentane-1,2,3,4-tetrol (1S,2S,3R)-1,2,3-三羟基-4-环丙烯2,3-环己基缩酮 1D-(1,2,3,4/5)-4-amino-1,2-O-isopropylidene-5-(methylsulfanyl)-3-O,4-N-(2,2,2-trichloroethylidene)cyclopentane-1,2,3-triol (3R,4R,5S)-5-acetoxy-4-acetylamino-3-tert-butyldimethylsilyloxy-1-cyclopentene (1S,4R,5R)-5-acetylamino-4-tert-butyldimethylsilyloxy-2-cyclopenten-1-ol (+)-tetraacetylmannostatin A (3S,4R,5S)-4-acetylamino-3-tert-butyldimethylsilyloxy-5-ethoxycarbonyloxy-1-cyclopentene (3S,4S,5S)-4-acetylamino-5-tert-butyldimethylsilyloxy-3-methylthio-1-cyclopentene (1R,2R,3R,4R,5S)-1-(methylthio)-2,3,4-triacetoxy-5-(N-((R)-acetoxyphenylacetyl)amino)cyclopentane (1R,2R,5S)-1-(methylthio)-2-hydroxy-5-(N-((R)-hydroxyphenylacetyl)amino)cyclopent-3-ene (1R,2R,5S)-1-(methylthio)-2-acetoxy-5-(N-((R)-acetoxyphenylacetyl)amino)cyclopent-3-ene