吉伏曲林

CAS号：107266-06-8

英文名：8-fluoro-2-(3-pyridin-3-ylpropyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole

分子式

C19H20FN3

熔点

密度

1.227g/cm3

分子量

309.381

沸点

498ºC at 760mmHg

溶解度

信号词

危险品标志

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化合物简介

Gevotroline (WY-47,384) is an atypical antipsychotic with a tricyclic structure which was under development for the treatment of schizophrenia by Wyeth-Ayerst. It acts as a balanced, modest affinity D2 and 5-HT2 receptor antagonist and also possesses high affinity for the sigma receptor. It was well-tolerated and showed efficacy in phase II clinical trials but was never marketed.

基本信息

中文名称

吉伏曲林

英文名称

8-fluoro-2-(3-pyridin-3-ylpropyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole

中文别名

英文别名

Gevotrolinum [INN-Latin]、Gevotroline [INN]、GEVOTROLINE HYDROCHLORIDE、8-fluoro-2,3,4,5-tetrahydro-2-[3-(3-pyridinyl)propyl]1H-pyrido[4,3-b]indole、Gevotrolinum、Gevotrolina、GEVOTROLINE

CAS号

107266-06-8

分子式

C19H20FN3

分子量

309.381

精确质量

309.164

PSA

31.92

LOGP

3.6308