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ChemeGen ChemeGen PROTAC Bcl2 degrader-1 纯度:98% CAS:2378801-85-3 (1mg/瓶) C110081 2378801-85-3
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¥6490
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PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC, which potently and selectively induces the degradation of Bcl-2 (IC50, 4.94 μM; DC50, 3.0 μM) and Mcl-1 (IC50, 11.81 μM) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1.
