化合物简介
Tienilic acid (INN and BAN) or ticrynafen (USAN) is a loop diuretic drug with uric acid-lowering (uricosuric) action, formerly marketed for the treatment of hypertension. It was approved by FDA on May 2, 1979, and withdrawn in 1982, after case reports in the United States indicated a link between the use of ticrynafen and hepatitis.
基本信息
中文名称
替宁酸
英文名称
tienilic acid
中文别名
2,3-二氯-4-(2-噻吩甲酰基)苯氧基乙酸、噻吩利尿酸、2-(2,3-二氯-4-(噻吩-2-羰基)苯氧基)乙酸
英文别名
[2,3-dichloro-4-(2-thenoyl)phenoxy]acetic acid、[2,3-dichloro-4-(thiophene-2-carbonyl)-phenoxy]-acetic acid、Thienylic acid、Ticrex、Diflurex、Acido tienilico、2-[2,3-dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid、TienilicAcid、Tienilico acido、Acidum tienilicum、2,3-dichloro-4-(thien-2-ylcarbonyl)-phenoxyacetic acid、Tienilic acid、Ticrynafen、Acide tienilique、Selacryn、Ticrynafen Tienylic acid [2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy]-acetic acid
CAS号
40180-04-9
分子式
C13H8Cl2O4S
分子量
331.171
精确质量
329.952
PSA
91.84
LOGP
3.7493
编号系统
UNII
HC95205SY4
物化性质
密度
1.532g/cm3
沸点
534.6ºC at 760 mmHg
熔点
148-149ºC
闪点
277.1ºC
折射率
1.632
储存条件
-20ºC Freezer
安全信息
海关编码
2934999090
