化合物简介
ZK-93426 (ethyl-5-isopropoxy-4-methyl-beta-carboline-3-carboxylate) is a drug from the beta-carboline family. It acts as a weak partial inverse agonist of benzodiazepine receptors, meaning that it causes the opposite effects to the benzodiazepine class of drugs and has anxiogenic properties, although unlike most benzodiazepine antagonists it is not a convulsant and actually has weak anticonvulsant effects. In human tests it produced alertness, restlessness and feelings of apprehension[clarification needed], and reversed the effect of the benzodiazepine lormetazepam. It was also shown to produce nootropic effects and increased release of acetylcholine.
基本信息
中文名称
Zk 93426盐酸盐
英文名称
4-Methyl-5-(1-methylethoxy)-9H-pyrido[3,4-b]indole-3-carboxylicacidethylesterhydrochloride
中文别名
英文别名
CAS号
89592-45-0
分子式
C18H21ClN2O3
分子量
348.824
精确质量
348.124
PSA
64.21
LOGP
4.7904