化合物简介
Pitolisant (INN) or tiprolisant (USAN) is a histamine receptor inverse agonist/antagonist selective for the H3 subtype. It has stimulant and nootropic effects in animal studies, and may have several medical applications, having been researched for the treatment of narcolepsy, for which it has been granted orphan drug status in the EU and US. It is currently in clinical trials for schizophrenia and Parkinson's disease.
基本信息
中文名称
Ciproxidine; 1-[3-[3-(4-氯苯基)丙氧基]丙基]哌啶盐酸盐
英文名称
1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine,hydrochloride
中文别名
英文别名
Pitolisant hydrochloride、Piperidine,1-[3-[3-(4-chlorophenyl)propoxy]propyl]-,hydrochloride、Ciproxidine
CAS号
903576-44-3
分子式
C17H27Cl2NO
分子量
332.308
精确质量
331.147
PSA
12.47
LOGP
4.9051
编号系统
UNII
YV33CH63HI