化合物简介
Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) is an intermediate in the formation of purines. The conversion of ATP, L-aspartate, and 5-aminoimidazole-4-carboxyribonucleotide (CAIR) to 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide, ADP, and phosphate by phosphoribosylaminoimidazolesuccinocarboxamide synthetase (SAICAR synthetase) represents the eighth step of de novo purine nucleotide biosynthesis.
基本信息
中文名称
(2S)-2-[[5-氨基-1-[(2R,3R,4S,5R)-3,4-二羟基-5-(膦酰氧基甲基)四氢呋喃-2-基]咪唑-4-羰基]氨基]丁二酸
英文名称
SAICAR
中文别名
英文别名
5-Amino-4-imidazole-N-succinocarboxamide ribonucleotide、Succino-AICAR、SAICAriboside、(2S)-2-[[5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]imidazole-4-carbonyl]amino]butanedioic acid
CAS号
3031-95-6
分子式
C13H19N4O12P
分子量
454.283
精确质量
454.074
PSA
277.29
LOGP
-1.9925
编号系统
UNII
K1PVR64RIF
