化合物简介
A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
基本信息
中文名称
P-羟基阿伐他汀内酯
英文名称
5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N-(4-hydroxyphenyl)-4-phenyl-2-propan-2-ylpyrrole-3-carboxamide
中文别名
4-羟基阿托伐他汀内酯
英文别名
5-(4-Fluorophenyl)-N-(4-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide、4-Hydroxy Atorvastatin Lactone、UNII-1316I46GEX
CAS号
163217-70-7
分子式
C33H33FN2O5
分子量
556.624
精确质量
556.237
PSA
100.79
LOGP
6.5721
编号系统
MDL号
MFCD00936958
物化性质
熔点
103-106°C
