化合物简介
Vicriviroc, previously named SCH 417690 and SCH-D, is a pyrimidine CCR5 entry inhibitor of HIV-1. It was developed by the pharmaceutical company Schering-Plough. Merck decided to not pursue regulatory approval for use in treatment-experienced patients because the drug did not meet primary efficacy endpoints in late stage trials. Clinical trials continue in patients previously untreated for HIV.
基本信息
中文名称
1-[(4,6-二甲基-5-嘧啶基)羰基]-4-[(3S)-4-[(1R)-2-甲氧基-1-[4-(三氟甲基)苯基]乙基]-3-甲基-1-哌嗪基]-4-甲基哌啶马来酸盐
英文名称
Vicriviroc Maleate
中文别名
英文别名
vicriviroc Maleate salt、Unii-ep3qg127N9、SCH-D、VICRIVIROC MALEATE: SCH-D
CAS号
599179-03-0
分子式
C32H42F3N5O6
分子量
649.701
精确质量
649.309
PSA
136.4
LOGP
4.0262
编号系统
UNII
EP3QG127N9
物化性质
沸点
608.1ºC at 760mmHg