合成路线
500225-58-1
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克拉屈滨
CAS号：4291-63-8
英文名：cladribine
分子式：C10H12ClN5O3
分子量：285.687
上游原料
2-氯-6-氨基嘌呤
2-chloro-6-(2-pentylimidazol-1-yl)purine
2-chloro-6-amino-9-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-β-D-ribofuranosyl]-purine
2-chloro-9-((6aR,8R,9aS)-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-9H-purin-6-amine
9-(3,5-di-O-benzoyl-2-deoxy-β-D-erythro-pentofuranosyl)-2-chloro-6-O-(6-methylbenzenesulfonyl)purine
2-chloro-9-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-6-(2-propylimidazol-1-yl)purine
2-chloro-6-(2-propylimidazol-1-yl)purine
2-氯腺嘌呤核苷
2-chloro-9-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-6-(2-pentylimidazol-1-yl)purine
2,6-二氯-9-(3,5-二-O-对甲苯甲酰基-2-脱氧-beta-D-赤式-呋喃戊糖基)嘌呤
2'-脱氧鸟苷水合物
1-乙酰基-2,3,5-三苯甲酰氧基-1-beta-D-呋喃核糖
2-chloro-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenosine
2-amino-9-(3,5-di-O-benzoyl-2-deoxy-β-D-erythro-pentofuranosyl)-6-chloropurine
9-(3,5-di-O-benzoyl-2-deoxy-β-D-erythro-pentofuranosyl)-2,6-dichloropurine
2,6-二氯嘌呤-2’-脱氧核苷
2-chloro-6-trimethylsilylamino-9-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-β-D-ribofuranosyl]-purine
2'-脱氧-3',5'-二-O-乙酰基鸟苷
9-(3,5-di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-2-amino-6-O-(2,4,6-triisopropylbenzenesulfonyl)purine
O-((6aR,8R,9R,9aR)-8-(6-amino-2-chloro-9H-purin-9-yl)-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-9-yl) O-phenyl carbonothioate
1-Alpha-氯-3,5-二-O-对甲苯甲酰基-2-脱氧-D-呋喃核糖
6-氯-9-(3,5-二-O-乙酰基-2-脱氧-beta-D-赤式-呋喃戊糖基)-9H-嘌呤-2-胺
2',3',5'-三-O-乙酰基-2-氯腺苷
2'-O-[phenoxy(thiocarbonyl)]-3',5'-O-triacetyl-2-chloroadenosine
6-amino-2-chloro-9-(2'deoxy-3',5'-di-O-acetyl-β-D-erythro-pentofuranosyl)-9H-purine
2’,3’,5’-tri-O-benzoyl-β-D-ribofuranosyl-2,6-dichloropurine
3',5'-O-triacetyl-2-chloroadenosine
甲醇
2,6-二氯嘌呤
2,6-di-chloro-9-(3',5'-di-O-p-methoxybenzoyl-2'-deoxy-D-ribofuranosyl)purine
2-amino-9-(3,5-di-O-benzoyl-2-deoxy-β-D-erythro-pentofuranosyl)-6-O-(2,4,6-triisopropylbenzenesulfonyl)purine
9-(3,5-di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-2,6-dichloropurine
2-chloro-N6,N6-dibenzoyl-3',5'-O-dibenzoyl-2'-deoxyadenosine
3',5'-di-O-benzoyl-2'-deoxyguanosine
2-amino-9-(3,5-di-O-benzoyl-2-deoxy-β-D-erythro-pentofuranosyl)-6-O-(4-methylbenzenesulfonyl)purine
胸苷
9-(3,5-di-O-benzoyl-2-deoxy-β-D-erythro-pentofuranosyl)-2-chloro-6-O-(2,4,6-triisopropylbenzenesulfonyl)purine
